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Which ONE of the following combinations of molecular masses of polypeptides are obtained from purified human IgM when analysed on sodium dodecyl suplhate polyacrylamide gel electrophoresis (SDS-PAGE) under reducing conditions?\t55 kDa, 15 kDa (B) 70 kDa, 25 kDa, 15 kDa (C) 55 kDa, 25 kDa (D) 155 kDa

Dhwani shah , 6 Years ago
Grade 12
anser 1 Answers
Arun

Last Activity: 6 Years ago

IgM is the major antibody produced in the primary immune response and it exists as part of the B-cell antigen receptor on the surface of B cells, and as a secreted glycoprotein. Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) is used to obtain the combinations of molecular masses of polypeptides from purified human IgM. The combinations obtained from SDS-PAGE are 70kDa, 25kDa and 15kDa.
So, the answer is B.

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