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Why aromatic primary amines cannot be prepard by Gabriel phthalimide synthesis?

aditya kashyap , 10 Years ago
Grade upto college level
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Gaurav

Last Activity: 9 Years ago

Hello Student
Gabrielphthalimide synthesis is used for the preparation of aliphatic primary amines. It involves nucleophilic substitution (SN2) of alkyl halides by the anion formed by the phthalimide. But aryl halides do not undergo nucleophilic substitution with the anion formed by the phthalimide.

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